Luina Bio is highly experienced in working with strict anaerobic cultures, especially to produce anaerobic fermentation products.

Luina Bio is a world leader in the culture of anaerobic bacteria. We have developed and produced at large scale in GMP a large number of facultative and strict anaerobes for customers worldwide. These bacteria have then been used as live biotherapeutics in a number of clinical studies in the USA, Europe, and Australia. Please find below a list of the genera we have successfully grown:

AerobesFacultative AnaerobesStrict Anaerobes
Acetobacter
Curtobacterium
Lysobacter
Rhodococcus
Acinetobacter
Deinococcus
Neisseria
Nocardia
Candida
Streptomyces
Saccharomyces
Corynebacterium
Xanthomonas
Micrococcus
Bacillus
Escherichia
Staphylococcus
Bifidobacterium
Streptococcus
Haemophilus
Prevotella
Klebsiella
Lactobacillus
Proteus
Serratia
Lactococcus
Pseudomonas
Akkermansia
Dorea
Roseburia
Ruminococus
Bacteroides
Eubacterium
Faecalibacterium
Odoribacter
Christensenella
Propinobacterium
Clostridium

Luina Bio fermentation and related services include:

  • Anaerobic cell bank preparation and qualification
  • Anaerobic fermentation from 5L up to 500L
  • Anaerobic lyophilization of live cultures
  • Anaerobic mid-stream and downstream processing
  • Anaerobic product packaging  
  • Fermentation and subsequent downstream purification
  • Upscale and downscale fermentation optimization

Our manufacturing processes can be operated in numerous modes (e.g., batch, fed batch, and perfusion) and we offer a full suite of manufacturing including whole cell preparations, recombinant products from microbial hosts, and naturally produced cellular products. Processing can be carried out as either non-GMP or GMP.

If you need a customized anaerobic fermentation service not listed here, please ask.